I have an HP ScanJet 5300C scanner and have had no luck getting it to run on Mac OS X after 10.3 Panther, Windows Server 2003, and Ubuntu Hardy Heron. After I upgraded to Ubuntu Karmic Koala, the XSane Image Scanner applications would scan a preview but would not actually save the image. (That’s more progress than I have had for a few years.) Next, I installed Simple Scan, which scanned and saved the image nicely. The program is a little simpler than I would like, but it beats the complexity of XSane. More importantly, it worked.